Try a different computer (if available) and see if the USB drive works okay.

And, various factors including sudden power failure, virus invasion, bad sectors, can cause this issue. External USB HDD not recognized in Windows 10 when connecting through USB. can't be opened and accessed is of common occurrence. In general, the error that partitions on external hard drive, USB flash drive, SD card, etc. In case it is due to a permission problem, you can try opening the pen drive in administrator mode. Once you have access to the keyboard, make sure you pull it out without causing any damage to the insides of the laptop. A little research needs to be done on opening up the laptop. In case you do not have a linux based OS, then you will have to try to find the cause of inaccessibility in windows. All things done, the final thing you might need to do is replace the keyboard. The best way is to open the pen drive in a Linux based operating system. Dangerous virus may completely vanish USB drive data Improper handling or using USB drive on various devices may lead to its file system corruption. Let us discuss possible reasons behind USB drive that is not showing any data: Harmful virus attacks become one of the major reasons for USB drive showing no data. You can try to update or reinstall the driver for pen drive to see whether the problem is solved. If the pen drive is not showing up in Disk Management but in Device Manger, outdated or incompatible device driver could be the reason of this problem. Frequently Asked Questions Why is my pen drive not working?

What to do if pendrive is not opening